Dr Costanzo earned his BA in Economics and Spanish from Lehigh University and worked in business before changing careers and entering medical school. After completing the Bryn Mawr postbaccalaureate program, he attended Jefferson Medical College in Philadelphia. He completed his Internal Medicine Residency at the University of Michigan and his Gastroenterology fellowship at Cooper University Hospital.

Dr Costanzo is an avid fitness and nutrition enthusiast. He holds an L1 CrossFit trainer certification. He has professional interests in nutritional counseling and irritable bowel syndrome. He is proficient in Spanish. He lives near Scranton with his wife and daughter.